It is the eighth successive year that Barcelona have reached the last 16 of the Champions League and they have only failed to advance to the quarter-finals twice - but on both occasions they were eliminated by English clubs - Chelsea in 2005 and Liverpool in 2007.
Barcelona's Argentine forward Lionel Messi scored four goals against Arsenal in the home leg of last season's quarter-final, including a first half hat-trick in just over 20 minutes, but he has only found the net in two of the 14 Champions League games he has played against teams from England. The other was the 2009 final against Manchester United when he scored the late second goal in Barca's 2-0 victory.
Barcelona have won their last seven Champions League home games, scoring 20 goals and conceding only two.
Arsenal, like Barcelona, have scored in all six matches between the two clubs so have good reason to expect to nab an away goal at the Camp Nou.
Arsenal have lost five of their last six Champions League away matches and returned from Spain defeated after seven of their last 11 visits there.
Arsenal striker Robin van Persie, who scored in the first leg, has found the net in six of his last nine Champions League appearances.